Hydroxychloroquine? Nah, says NEJM.

 

Officially, (if you needed official confirmation), as published in the highly regarded medical journal, NEJM, a study finds hydroxychloroquine is completely ineffective in treating COVID. In fact, it could be harmful- some people taking the drug have more heart and liver problems.

“Among patients hospitalized with mild-to-moderate Covid-19, the use of hydroxychloroquine, alone or with azithromycin, did not improve clinical status at 15 days as compared with standard care. “

“In this open-label, multicenter, randomized, controlled trial involving hospitalized patients with confirmed mild-to-moderate Covid-19, a 7-day course of hydroxychloroquine either with azithromycin or alone did not result in better clinical outcomes as measured by a seven-level ordinal scale at 15 days. There was also no effect on any of the secondary outcomes. Occurrence of any adverse event, elevation of liver-enzyme levels, and prolongation of the QTc interval was more frequent in patients receiving hydroxychloroquine with azithromycin or hydroxychloroquine alone than in those receiving neither agent.”

https://www.nejm.org/doi/full/10.1056/NEJMoa2019014

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